Our next product Carcinome, is a gene expression test to detect the presence of non-melanoma skin cancers using skin samples collected with our Adhesive Skin Collection Kit. Non-melanoma skin cancer includes basal cell carcinoma and squamous cell carcinoma. We have identified differentially expressed genes that allow the identification of these cancers, and we are currently conducting clinical trials to validate this test.
Non-Melanoma Skin Cancers
Nearly 5.5 million basal and squamous cell carcinoma skin cancers are diagnosed each year making skin cancer by far the most common of all types of cancer. The majority of these cancers occur in cosmetically sensitive areas such as the head, neck, and face. The number of skin cancer cases is increasing due to better skin cancer detection, people living longer, and increased sun exposure.
Basal Cell Carcinoma
More than 80% of skin cancers are basal cell carcinomas. These cancers usually develop in sun-exposed areas, especially the head and neck, and tend to grow slowly. It’s very rare for a basal cell cancer to spread to other parts of the body. If left untreated, it can grow into nearby areas and invade other tissues beneath the skin. If not removed completely, basal cell carcinoma can recur in the same place on the skin. People who have had basal cell skin cancers are also more likely to get new ones in other places.
Basal cell carcinomas may look like:
- Red patches
- Pink growths
- Shiny bumps or scars
- Open sores
Squamous Cell Carcinoma
About 10% of skin cancers are squamous cell carcinomas. These cancers also commonly appear on sun-exposed areas of the body such as the face, ears, neck, lips, and backs of the hands. They can also develop in scars or chronic skin sores elsewhere. Squamous cell cancers are more likely to grow into deeper layers of skin and spread to other parts of the body than basal cell cancers, although this is still uncommon.
Squamous cell carcinomas may look like:
- Scaly red patches
- Growth with a depression in the center
- Open sores