Meet the Smart StickerTM that is changing everything.
There’s a reason doctors had to cut your skin to test for melanoma. They didn’t have another way. Now, thanks to this smart sticker, they do.
The DermTech Smart StickerTM gently lifts skin cells off the surface of your mole — no need for a scalpel. The sticker is pressed on the mole, then quickly lifted off, carrying your skin’s genomic material with it.
Now doctors can see beyond a biopsy1 with an accurate, non-invasive test: The DermTech Melanoma Test.2
This isn’t just a different test. This is revolutionary.
Traditional melanoma detection methods are visual and subjective. Doctors use their eyes to see physical changes to a mole, and the cells within it.
A groundbreaking innovation now lets us look beyond your skin’s surface, deep within your genes, for markers that indicate the likelihood of disease objectively.
And it’s all accomplished with cells gently lifted off the surface of your mole with a highly specialized smart sticker.
We call it Precision Dermatology.
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A Better Way to Find Melanoma Early3,4
The DermTech Melanoma Test can detect changes in your skin’s RNA and DNA so that melanoma can be caught earlier—a critical factor in beating the disease.5,6
A negative DermTech Melanoma Test result means there is a greater than 99% probability that the suspicious mole is not melanoma.6
Our DermTech Smart Sticker™ collects skin cells non-invasively. This means no unnecessary pain, scalpel, cutting, or scarring.3,7
“There is no question that early detection saves lives, and this tool revolutionizes our ability to find melanoma earlier.”
— Laura Ferris, M.D., Ph.D.
The Tech in DermTech
The DermTech Smart StickerTM lifts skin cells from your suspicious skin spot. The sticker is simply pressed onto the spot, lifted off, and then sent to our Gene Lab. This can be done at your doctor’s office, remotely with supervision, or via a telehealth appointment (where available).
The Gene Lab
Your sample arrives at the DermTech Gene Lab where it will be tested for genomic markers associated with melanoma. Seeing deeper into the genomic makeup of your skin cells gives your doctor the ability to diagnose melanoma earlier.
At the Gene Lab, a DermTech patented process tests for the presence of elevated expression levels of two genes proven to correlate with melanoma, LINC00518 and PRAME, as well as DNA mutations in a gene called TERT.5,8
DermTech It via Remote Collection
DermTech in the News
Read how DermTech is “shifting the melanoma landscape.”
- Biopsy is inclusive of the melanoma diagnostic pathway and includes both surgical biopsy and histopathological evaluation.
- The DermTech Melanoma Test consists of two laboratory tests performed on a single tissue collection: (i) the Pigmented Lesion Assay (PLA) test, is covered by Medicare; and (ii) plus (using remaining genomic material, if available, after the PLA is performed), the plus add-on test does not yet have Medicare coverage. The PLA test may be ordered without the plus add-on.
- Compared to biopsy. Ferris LK et al. Utility of a noninvasive 2-gene molecular assay for cutaneous melanoma and effect on the decision to biopsy. JAMA Dermatol. 2017;153(7):675-680.
- Compared to biopsy. Elmore JG et al. Pathologists’ diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study. BMJ. 2017;357:j2813.
- Gerami P et al. Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma. J Am Acad Dermatol. 2017;76(1):114-120.
- Melanoma early detection. Seattle Cancer Care Alliance website. https://www.seattlecca.org/…. Accessed October 28, 2020
- J Mol Biol. 1981 Oct 15;152(1):153-61. doi: 10.1016/0022-2836(81)90099-1.
- Ferris LK et al. Impact on clinical practice of a non-invasive gene expression melanoma rule-out test: 12-month follow-up of negative test results and utility data from a large US registry study. Dermatol Online J. 2019;25(5).
- Jackson R et al. SKIN. 2020;5(1):105-110.
- Robinson J, et al. SKIN. 2020;5(1):248-251.