DermTech Smart Stickers™ can non-invasively detect RNAs that are associated with non-melanoma skin cancer
Current diagnosis of NMSC relies on a visual assessment of suspicious lesions followed by a surgical skin biopsy for histopathologic review. We investigated whether non-invasive collection of skin tissue and subsequent genomic analysis could properly classify NMSC.
Identification of Novel Gene Classifiers to Non-Invasively Diagnose Non-Melanoma Skin Cancer
Non-melanoma skin cancers (NMSC) are the most common types of skin cancer and include both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). NMSC primarily form on sun exposed skin including the head, face, neck, arms, and hands. BCC accounts for >75% of NMSC cases; however, SCC is more aggressive and may occur in other locations as well.
A Non-Invasive Gene Expression Assay for Cutaneous Basal Cell and Squamous Cell Carcinoma
BCC-SCC 2018 AAD ABSTRACT
Fall Clinical Dermatology Abstract- Basal and Squamous Cell Gene Classifier
Reproducibility and Accuracy of Cross Platform RT-qPCR Testing for the Detection of mRNA from Surface Squamous Cells Overlying Pigmented Skin Lesions
H.S. Robin, T.J. Palmer, J.P. Alsobrook. (2013) The Journal of Molecular Diagnostics