Understanding Test Performance Measures

The DermTech Melanoma Test is a melanoma rule-out test designed for maximum sensitivity and NPV to minimize the possibility of missing a melanoma.
Test Performance Measures
understanding ldt metrics

Reference: Monaghan TF, et al. Medicina (Kaunas). 2021;57(5)

The DermTech Melanoma Test (Pigmented Lesion Assay) Validation Study Established Its High Sensitivity and NPV metrics.

The prospective study simultaneously collected samples via non-invasive skin collection (Smart Stickers) and surgical biopsy. DMT results (LINC/PRAME expression) were compared to histopatghologic diagnosis by three expert dermatopathologists (11% discordance rate).

DermTech Melanoma Test Validation Metrics:

LINC/PRAME Analysis

%

NPV

%

Sensitivity

%

Specificity