Publications

Inflammatory Disease

Inflammatory Disease Publications

Non-Invasively Stratifying Atopic Dermatitis Patients Based on Inflammatory Genes

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by significant barrier disruption and intense pruritus. In recent years, there has been a growing number of targeted therapies in clinical development with a predominant focus on antagonizing Th2-mediated inflammation; however, these therapies are effective (IGA 0/1) in less than 50% of AD patients.

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Non-Invasive Gene Expression Analysis Assay for Psoriasis

Significant progress has been made in the treatment of moderate to severe psoriasis through blocking key cytokines such as TNF-α, IL-17A and IL-23 involved in the pathogenesis and progression of the disease. However neither the marketed drugs nor the drug candidates in development show complete response rates.

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