Publications

To optimize data translatability, there is a need to define a robust operating protocol for epidermal tissue collection, including the definition of the least invasive sampling tape. In this study, we have compared the Smart Sticker (DermTech) to the D-squame skin sampling disc (CuDerm) by collecting non-overlapping adjacent volar forearm skin of twenty healthy volunteers.

A number of diagnoses in clinical dermatology are currently histopathologically confirmed and this image recognition-based confirmation generally requires surgical biopsies. The increasing ability of molecular pathology to corroborate or correct a clinical diagnosis based on objective gene expression, mutation analysis, or molecular microbiome data is on the horizon and would be further supported by a tool or procedure to collect samples non-invasively. This study characterizes such a tool in form of a ‘bladeless’ adhesive patch-based skin biopsy device.